Lepromatous Leprosy: Dapsone Resistance
نویسندگان
چکیده
منابع مشابه
Low dose dapsone therapy in lepromatous leprosy.
U n der the conditions of this s tudy, dapsone in d oses of 5 mg and 10 mg daily when ad ministered to p atients with lepromat ous leprosy is an ineffe ctive therapy in terms of killing and elimin ation of My co. leprae from human skin and b one marrow . A real danger of facili tating the emergence of resistant bacilli exists . Therefore , un til there is more evidence from long term therapeuti...
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In 1972/73 a se ries of patients with early untreated lepromatous leprosy in South I ndia we re studied and the clinicai, bacteriological and histopathological findings in the nose have been reported. The involvement of nasal tissues and the enormous numbers of viable b acilli escaping from the nose into t he environ ment were of such clinicai and epidemiological imp ort ance that it was clearl...
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While u nder treatment with'dapso ne for lepromatous leprosy , a 5 0-year-old male Greek Cypriot presented with multiple widespread lesions of a bizarre type, many of them freely ulceTating. Iinically and histologically, peripheral nerves were little affected, but biopsy s mples of skin and ulcers contained enormous numbers of leprosy bacilli. M ouse footpad inoculation of the bacilli from skin...
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Although the preventive action of dapsone against P. falciparum malaria was known for many years, there was no report about the incidence of P. falciparum malaria in leprosy patients treated with dapsone, especially from areas of Southeast Asia where both leprosy and malaria are endemic. Therefore, two clinic-based malaria surveys were undertaken at a gap of 12 years, comprising 506 lepromatous...
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A 48-year-old soldier presented with 3 small leprosy lesions localized over the flexor area of the forearm. There was no nerve thickening and clinically the lesions looked like borderline-tuberculoid leprosy. However, these lesions demonstrated a bacteriological index (BI) of 4+ while no acid-fast bacilli (AFB) could be demonstrated from any other site of the body. A lepromin test was negative....
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ژورنال
عنوان ژورنال: Proceedings of the Royal Society of Medicine
سال: 1976
ISSN: 0035-9157
DOI: 10.1177/003591577606900606